Nuclear pore complexes: dynamics in unexpected places

Citation
Sk. Lyman et L. Gerace, Nuclear pore complexes: dynamics in unexpected places, J CELL BIOL, 154(1), 2001, pp. 17-20
Citations number
24
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Cell & Developmental Biology
Journal title
JOURNAL OF CELL BIOLOGY
ISSN journal
0021-9525 → ACNP
Volume
154
Issue
1
Year of publication
2001
Pages
17 - 20
Database
ISI
SICI code
0021-9525(20010709)154:1<17:NPCDIU>2.0.ZU;2-3
Abstract
In vivo studies on the dynamics of the nuclear pore complex (NPC) in yeast suggested that NPCs are highly mobile in the nuclear envelope. However, new evidence indicates that in mammalian cells NPCs are stably attached to a f lexible lamina framework, but a peripheral component can exchange rapidly w ith an intranuclear pool.