Intramuscular spindle cell lipoma: Case report and review of the literature

Citation
K. Horiuchi et al., Intramuscular spindle cell lipoma: Case report and review of the literature, PATHOL INT, 51(4), 2001, pp. 301-304
Citations number
21
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Medical Research Diagnosis & Treatment
Journal title
PATHOLOGY INTERNATIONAL
ISSN journal
1320-5463 → ACNP
Volume
51
Issue
4
Year of publication
2001
Pages
301 - 304
Database
ISI
SICI code
1320-5463(200104)51:4<301:ISCLCR>2.0.ZU;2-Z
Abstract
Spindle cell lipoma (SCL) is a relatively rare adipocytic neoplasm and is h istologically characterized by a mixture of uniform spindle cells and matur e fat cells. It occurs predominantly in male patients aged 45-65 years, and in most cases it arises in the subcutaneous tissue of the neck or shoulder . Although the neoplasm sometimes affects unusual sites, only three cases h ave been reported in which the lesion was intramuscular. Here we present a case of SCL arising in skeletal muscle; to our knowledge, the first report in 10 years. the tumor occurred in the neck of a 50-year-old male patient. Magnetic resonance imaging (MRI) revealed a lipomatous tumor within the rig ht trapezius muscle. The tumor was localized beneath the fascia and was exc ised completely at surgery. Histologically, the tumor was typical of a spin dle cell lipoma with no evidence of malignancy. An immunohistochemical stud y revealed all spindle cells were strongly positive for CD34. Differential diagnosis is discussed with a review of the literature.