A long-term lifetime amperometric glucose sensor with a perfluorocarbon polymer coating

Citation
T. Matsumoto et al., A long-term lifetime amperometric glucose sensor with a perfluorocarbon polymer coating, BIOSENS BIO, 16(4-5), 2001, pp. 271-276
Citations number
10
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Biotecnology & Applied Microbiology
Journal title
BIOSENSORS & BIOELECTRONICS
ISSN journal
0956-5663 → ACNP
Volume
16
Issue
4-5
Year of publication
2001
Pages
271 - 276
Database
ISI
SICI code
0956-5663(200106)16:4-5<271:ALLAGS>2.0.ZU;2-K
Abstract
We have developed an amperometric glucose sensor whose electrodes are coate d with a four-layered membrane: 3-aminopropyltriethoxysilane (gamma -APTES) , Nafion((R)), glucose oxidase (GOX), and perfluorocarbon polymer (PFCP). T ests demonstrate the sensor's ability to accurately and successively determ ine glucose concentrations ranging from 2.8 to 167 mM, over a 66 day period with no increase in response time, while remaining imperviousness to the e ffects of interference species (2.8 mM ascorbic acid, 0.3 mM uric acid, 0.3 mM p-acetaminophen). Furthermore, tests on diabetic urine samples showed a n excellent correlation coefficient of 0.985 (gamma = 1.04x + 4.73, n = 30) between sensor results and those of Glucose-Dehydrogenase clinical laborat ory analyses. (C) 2001 Elsevier Science B.V. All rights reserved.