Evaluation of the severity of traumatic rhabdomyolysis using technetium-99m pyrophosphate scintigraphy

Citation
Hr. Chang et al., Evaluation of the severity of traumatic rhabdomyolysis using technetium-99m pyrophosphate scintigraphy, AM J NEPHR, 21(3), 2001, pp. 208-214
Citations number
17
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Urology & Nephrology
Journal title
AMERICAN JOURNAL OF NEPHROLOGY
ISSN journal
0250-8095 → ACNP
Volume
21
Issue
3
Year of publication
2001
Pages
208 - 214
Database
ISI
SICI code
0250-8095(200105/06)21:3<208:EOTSOT>2.0.ZU;2-T
Abstract
A quantitative scoring method was designed to assess the extent of muscle d amage. Technetium-99m pyrophosphate (Tc-99m-PYP) scintigraphy was performed for 9 patients experiencing crush injury in the Chichi (Taiwan) earthquake . The magnitude of muscle uptake of Tc-99m-PYP was graded as follows: grade 0, less than bone radioactivity (BRA); grade 1, equal to BRA; grade 2, hig her than BRA; or grade 3, greatly higher than BRA. The area of muscle injur y was estimated according to the rule of nines. The sum of the muscle injur y size multiplied by its corresponding grading was defined as the anterior or posterior score according to the anterior or posterior images. Each imag e was interpreted by two physicians and average anterior and posterior scor es were calculated. The muscle score was defined as the geometric mean of t he average anterior and posterior scores. Significant correlations were obt ained between the muscle score and duration of time trapped (r = 0.868, p < 0.01), peak serum creatine kinase level (r = 0.866, p < 0.01), peak serum phosphorus level (r = 0.877, p < 0.01) and number of hospital days (r = 0.8 75, p < 0.01). A negative correlation between the muscle score and blood pH (r = -0.706, p < 0.01) was also observed. We concluded that this scoring m ethod may be used as an adjunct for evaluating the locations of trauma and the severity of crush syndrome, and for predicting the duration of hospital stay. Copyright (C) 2001 S. Karger AG, Basel.