Reaction of isothiourea with 2,3-diaza-3-pentenedioic anhydride. A solid-phase synthesis of 3-amino-1,2,4-triazin-5(4H)-ones

Citation
Ry. Yang et Ap. Kaplan, Reaction of isothiourea with 2,3-diaza-3-pentenedioic anhydride. A solid-phase synthesis of 3-amino-1,2,4-triazin-5(4H)-ones, TETRAHEDR L, 42(27), 2001, pp. 4433-4435
Citations number
20
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
0040-4039 → ACNP
Volume
42
Issue
27
Year of publication
2001
Pages
4433 - 4435
Database
ISI
SICI code
0040-4039(20010702)42:27<4433:ROIW2A>2.0.ZU;2-K
Abstract
The first reported solid-phase synthesis of 3-amino-1,2,4-triazin-5(4H)-one s is described. Reactions of polymer-bound isothiourea with 2,3-diaza-3-pen tenedioic anhydride forms 3-amino-1,2,4-triazin-5(4H)-ones in good yields a nd high purity. (C) 2001 Elsevier Science Ltd. All rights reserved.