A normalized root-mean-square distance for comparing protein three-dimensional structures

Citation
O. Carugo et S. Pongor, A normalized root-mean-square distance for comparing protein three-dimensional structures, PROTEIN SCI, 10(7), 2001, pp. 1470-1473
Citations number
11
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Biochemistry & Biophysics
Journal title
PROTEIN SCIENCE
ISSN journal
0961-8368 → ACNP
Volume
10
Issue
7
Year of publication
2001
Pages
1470 - 1473
Database
ISI
SICI code
0961-8368(200107)10:7<1470:ANRDFC>2.0.ZU;2-O
Abstract
The degree of similarity of two protein three-dimensional structures is usu ally measured with the root-mean-square distance between equivalent atom pa irs. Such a similarity measure depends on the dimension of the proteins, th at is, on the number of equivalent atom pairs. The present communication pr esents a simple procedure to make the root-mean-square distances between pa irs of three-dimensional structures independent of their dimensions. This n ormalization may be useful in evolutionary and fold classification studies as well as in simple comparisons between different structural models.