Withanolides from Salpichroa origanifolia

Citation
Mc. Tettamanzi et al., Withanolides from Salpichroa origanifolia, J NAT PROD, 64(6), 2001, pp. 783-786
Citations number
11
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
0163-3864 → ACNP
Volume
64
Issue
6
Year of publication
2001
Pages
783 - 786
Database
ISI
SICI code
0163-3864(200106)64:6<783:WFSO>2.0.ZU;2-5
Abstract
Five new withanolides, 5 alpha ,6 alpha :22,26: 24,25-triepoxy-16 alpha ,26 -dihydroxy-18(13 --> 17)-abeo-ergosta-2, 13-dien-1-one (salpichrolide N, 1) , 5 alpha ,6 alpha :22,26:24,25-triepoxi-15 alpha ,26-dihydroxyergosta-2,16 -dien-1-one (salpichrolide L, 2), 5 alpha ,6 alpha :22,26-diepoxi-24,25,26- trihydroxy-17(13 --> 18)-abeo-ergosta-2,13,15,17-tetrarn-1-one (salpichroli de M, 3a), 5 alpha ,6 alpha :22,25:22,26-triepoxy-24-hydroxy-17(13 --> 18)- abeo-ergosta-2,13,15,17-tetraen-1-one (salpichrolide J, 4), and 5 alpha ,6 alpha :22,26-diepoxy-22,24,25-trihydroxy-17(13 --> 18)-abeo-ergosta-2,13,15 ,17-tetraen-1-one (salpichrolide K, 5), were isolated from the leaves of Sa lpichroa origanifolia and characterized by a combination of spectroscopic ( 1D and 2D NMR, MS) and chemical methods.