Synthetic derivatives of abietic acid with radical scavenging activity

Citation
Ma. Esteves et al., Synthetic derivatives of abietic acid with radical scavenging activity, J NAT PROD, 64(6), 2001, pp. 761-766
Citations number
28
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
0163-3864 → ACNP
Volume
64
Issue
6
Year of publication
2001
Pages
761 - 766
Database
ISI
SICI code
0163-3864(200106)64:6<761:SDOAAW>2.0.ZU;2-0
Abstract
In this work, studies on the arylation of anilines derived from dehydroabie tic acid, the main component of disproportionated rosin, are presented. The redox properties of the new diarylamines were investigated by cyclic volta mmetry, and their free radical scavenging activity was tested by reduction of the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical. Three of the diarylami nes with lower oxidation potential proved to be as active as isopropyldiphe nylamine (IPPD) and superior to tert-butylhydroxytoluene (BHT), both commer cially available synthetic antioxidants.