Stereochemical control of the reaction of chlorosilane with methyllithium by the addition of metal cyanide: Inversion by potassium cyanide and retention by copper(I) cyanide

Citation
K. Tamao et al., Stereochemical control of the reaction of chlorosilane with methyllithium by the addition of metal cyanide: Inversion by potassium cyanide and retention by copper(I) cyanide, SYNLETT, 2001, pp. 964-966
Citations number
8
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
0936-5214 → ACNP
Year of publication
2001
Pages
964 - 966
Database
ISI
SICI code
0936-5214(2001):<964:SCOTRO>2.0.ZU;2-1
Abstract
In the 1,4-dichlorotetrasilane derivative composed of disilane units bearin g two pentamethylene tethers, the substitution of a chlorine atom on the si licon atom by the methyl group during the reaction with methyllithium mainl y proceeds with inversion of configuration of the silicon atoms, (1) the yi eld being dramatically improved by the addition of potassium cyanide, and ( 2) the stereochemistry being changed to retention of configuration by the a ddition of copper(I) cyanide.