Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: An internationalconsensus

Citation
S. Ascioglu et al., Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stem cell transplants: An internationalconsensus, CLIN INF D, 34(1), 2002, pp. 7-14
Citations number
35
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL INFECTIOUS DISEASES
ISSN journal
1058-4838 → ACNP
Volume
34
Issue
1
Year of publication
2002
Pages
7 - 14
Database
ISI
SICI code
1058-4838(20020101)34:1<7:DOIFII>2.0.ZU;2-2
Abstract
During the past several decades, there has been a steady increase in the fr equency of opportunistic invasive fungal infections (IFIs) in immunocomprom ised patients. However, there is substantial controversy concerning optimal diagnostic criteria for these IFIs. Therefore, members of the European Org anization for Research and Treatment of Cancer/Invasive Fungal Infections C ooperative Group and the National Institute of Allergy and Infectious Disea ses Mycoses Study Group formed a consensus committee to develop standard de finitions for IFIs for clinical research. On the basis of a review of liter ature and an international consensus, a set of research-oriented definition s for the IFIs most often seen and studied in immunocompromised patients wi th cancer is proposed. Three levels of probability are proposed: "proven," "probable," and "possible." The definitions are intended for use in the con text of clinical and/or epidemiological research, not for clinical decision making.