Hepatosplanchnic oxygenation is better preserved during mild hypothermic than during normothermic cardiopulmonary bypass

Citation
N. Okano et al., Hepatosplanchnic oxygenation is better preserved during mild hypothermic than during normothermic cardiopulmonary bypass, CAN J ANAES, 48(10), 2001, pp. 1011-1014
Citations number
10
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Aneshtesia & Intensive Care","Medical Research Diagnosis & Treatment
Journal title
CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE
ISSN journal
0832-610X → ACNP
Volume
48
Issue
10
Year of publication
2001
Pages
1011 - 1014
Database
ISI
SICI code
0832-610X(200111)48:10<1011:HOIBPD>2.0.ZU;2-X
Abstract
Purpose: To assess and compare the effects of normothermic and mild hypothe rmic cardiopulmonary bypass (CPB) on hepatosplanchnic oxygenation. Methods: We studied 14 patients scheduled for elective coronary artery bypa ss graft surgery who underwent normothermic (> 35 degreesC; group I, n = 7) or mild hypothermic (32 degreesC; group II, n = 7) CPB. After induction of anesthesia, a hepatic venous catheter was inserted into the right hepatic vein to monitor hepatic venous oxygen saturation (ShvO(2)) and hepatosplanc hnic blood flow by a constant infusion technique that uses indocyanine gree n. Results: The ShvO(2) decreased from a baseline value in both groups during CPB and was significantly lower at ten minutes and 60 min after the onset o f CPB in group I (39.5 +/- 16.2% and 40.1 +/- 9.8%, respectively) than in g roup II (61.1 +/- 16.2% and 61.0 +/- 17.9%, respectively; P < 0.05). During CPB, the hepatosplanchnic oxygen extraction ratio was significantly higher in group I than in group II (44.0 +/- 7.2% vs 28.7 +/- 13.1%; P < 0.05). Conclusion: Hepatosplanchnic oxygenation was better preserved during mild h ypothermic CPB than during normothermic CPB.