Vertebrate somitogenesis

Authors
Citation
O. Pourquie, Vertebrate somitogenesis, ANN R C DEV, 17, 2001, pp. 311-350
Citations number
178
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Cell & Developmental Biology
Journal title
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY
ISSN journal
1081-0706 → ACNP
Volume
17
Year of publication
2001
Pages
311 - 350
Database
ISI
SICI code
1081-0706(2001)17:<311:VS>2.0.ZU;2-W
Abstract
In vertebrates, the paraxial mesoderm corresponds to the bilateral strips o f mesodermal tissue flanking the notochord and neural tube and which are de limited laterally by the intermediate mesoderm and the lateral plate. The p araxial mesoderm comprises the head or cephalic mesoderm anteriorly and the somitic region throughout the trunk and the tail of the vertebrates. Soon after gastrulation, the somitic region of vertebrates starts to become segm ented into paired blocks of mesoderm, termed somites. This process lasts un til the number of somites characteristic of the species is reached. The som ites later give rise to all skeletal muscles of the body, the axial skeleto n, and part of the dermis. In this review I discuss the processes involved in the formation of the paraxial mesoderm and its segmentation into somites in vertebrates.