The continuous recording of blood pressure in patients undergoing carotid surgery under remifentanil versus sufentanil analgesia

Citation
S. Mouren et al., The continuous recording of blood pressure in patients undergoing carotid surgery under remifentanil versus sufentanil analgesia, ANESTH ANAL, 93(6), 2001, pp. 1402-1409
Citations number
21
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Aneshtesia & Intensive Care","Medical Research Diagnosis & Treatment
Journal title
ANESTHESIA AND ANALGESIA
ISSN journal
0003-2999 → ACNP
Volume
93
Issue
6
Year of publication
2001
Pages
1402 - 1409
Database
ISI
SICI code
0003-2999(200112)93:6<1402:TCROBP>2.0.ZU;2-L
Abstract
We compared the hemodynamic stability during carotid endarterectomy of remi fentanil with that of sufentanil anesthesia. Fifty-six patients were random ly assigned into Remifentanil (n = 27) or Sufentanil (n = 29) groups. In th e Remifentanil group, IV propacetamol (2 g) and morphine (0.1 mg/kg) were i nfused 30 min before skin closure. In the Sufentanil group, patients receiv ed 2 g propacetamol. Beat-to-beat recordings of systolic arterial blood pre ssure (SBP) and heart rate (HR) were stored on a computer. The maximum and minimum values of BP and HR after induction, at intubation, during the surg ical procedure, and after the operation and the coefficients of variation o f SBP and HR were used as indices of hemodynamic stability. The coefficient s of variation of SBP and HR were similar in both groups during and after s urgery. However, at intubation, maximal SBP was higher in the Sufentanil gr oup (P < 0.05). Decreased propofol doses and isoflurane end-tidal concentra tions were used in the Remifentanil group. At recovery, a similar profile o f SBP and FIR was found in both groups. We conclude that intra- and posthem odynamic stability was similar with remifentanil or sufentanil in patients undergoing carotid endarterectomy. However, remifentanil was more effective for blunting the increase in SBP at intubation without increasing the bloo d pressure-decreasing effect of induction. Intraoperative remifentanil use was associated with a decreased amount of hypnotic drug administered.