Tethering and tickling: a new role for the phosphatidylserine receptor

Citation
S. Somersan et N. Bhardwaj, Tethering and tickling: a new role for the phosphatidylserine receptor, J CELL BIOL, 155(4), 2001, pp. 501-504
Citations number
18
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Cell & Developmental Biology
Journal title
JOURNAL OF CELL BIOLOGY
ISSN journal
0021-9525 → ACNP
Volume
155
Issue
4
Year of publication
2001
Pages
501 - 504
Database
ISI
SICI code
0021-9525(20011112)155:4<501:TATANR>2.0.ZU;2-9
Abstract
Several receptors are implicated in apoptotic cell (AC) uptake by phagocyti c cells; however, their relative dominance in mammalian systems remains to be established. New studies shed light on the role of the phosphatidyl seri ne (PS) receptor (PSR). Ligation of PSR by PS on AC surfaces is considered essential for signaling uptake of ACs that are tethered to phagocytes via o ther receptors.