Semi-continuous production of lauroyl kojic acid through lipase-catalyzed condensation in acetonitrile

Citation
T. Kobayashi et al., Semi-continuous production of lauroyl kojic acid through lipase-catalyzed condensation in acetonitrile, BIOCH ENG J, 9(2), 2001, pp. 85-89
Citations number
8
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Biotecnology & Applied Microbiology
Journal title
BIOCHEMICAL ENGINEERING JOURNAL
ISSN journal
1369-703X → ACNP
Volume
9
Issue
2
Year of publication
2001
Pages
85 - 89
Database
ISI
SICI code
1369-703X(200112)9:2<85:SPOLKA>2.0.ZU;2-B
Abstract
7-O-Lauroyl kojic acid was synthesized on some tens of grams scale through lipase-catalyzed condensation of kojic and lauric acids in acetonitrile usi ng a semi-continuous system where unreacted substrates were reused after th e product recovery. The acylation of kojic acid improved the solubility in hexane and soybean oil. The absorption spectra of lauroyl kojic acid chelat ed with ferric ion were observed in ethanol and soybean oil at various mola r ratios. The color tone of the complex of lauroyl kojic acid and Fe3+ was similar to that of the complex of unmodified kojic acid and Fe3+ in ethanol . (C) 2001 Elsevier Science B.V. All rights reserved.