Ckc. Loo et al., Intraabdominal follicular dendritic cell sarcoma - Report of a case with fine needle aspiration findings, ACT CYTOL, 45(6), 2001, pp. 999-1004
Citations number
14
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
BACKGROUND: Follicular dendritic cell sarcoma is a rare tumor derived from
dendritic cells of lymphoid follicles. Although it shows characteristic cyt
ologic, histologic and immunohistochemical features, it may be misdiagnosed
because of the lack of experience with this entity. There are few reports
in the cytologic literature describing this entity.
CASE: A left hypochondrial mass was found in an 80-year-old man who had a p
ast history of colonic carcinoma. A computed tomography-guided fine needle
aspiration biopsy was performed, and the findings were initially thought to
be compatible with metastatic carcinoma. The mass was excised, and a diagn
osis of follicular dendritic cell sarcoma was made.
CONCLUSION: Follicular dendritic cell sarcoma is characterized by loosely c
ohesive or syncytial groups of dendritic cells that show oval, vesicular nu
clei and ill-defined cytoplasm intimately admixed with small, mature lympho
cytes. The diagnosis can be confirmed by positive immunostaining for CD21 a
nd CD35 antigens and negative staining for cytokeratin. Unusual features in
our case were the presence of prominent plasma cells and intracytoplasmic,
periodic acid-Schiff stain, diastase-positive deposits, with the last not
described before.