Hemocompatibility of DLC coatings synthesized by ion beam assisted deposition

Citation
Dj. Li et al., Hemocompatibility of DLC coatings synthesized by ion beam assisted deposition, SCI CHINA E, 44(4), 2001, pp. 427-431
Citations number
18
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Engineering Management /General
Journal title
SCIENCE IN CHINA SERIES E-TECHNOLOGICAL SCIENCES
ISSN journal
2095-0624 → ACNP
Volume
44
Issue
4
Year of publication
2001
Pages
427 - 431
Database
ISI
SICI code
2095-0624(200108)44:4<427:HODCSB>2.0.ZU;2-3
Abstract
Ion beam-assisted diamond-like carbon (DLC) coatings have been used for gro wing the human platelet, fibrinogen, and albumin in the control environment in order to assess their hemocompatibility. The hard carbon films were pre pared on polymethylmethacrylate (PMMA) at room temperature using ion beam a ssisted deposition (IBAD). Raman spectroscopic analysis proved that the car bon films on PMMA are diamond-like with a higher fraction of sp(3) bonds in the structure of mixed sp(2) + sp(3) bonding. The blood protein adsorption tests showed that DLC coatings can adsorb more albumin and are slightly mo re fibrinogen than the PMMA chosen as a control sample. The platelets adher ed on DLC coatings were reduced significantly in number. These results indi cate good hemocompatibility of DLC coatings.