Autoimmune thyroid disease in women with breast carcinoma

Citation
J. Gogas et al., Autoimmune thyroid disease in women with breast carcinoma, EUR J SUR O, 27(7), 2001, pp. 626-630
Citations number
18
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Oncology
Journal title
EUROPEAN JOURNAL OF SURGICAL ONCOLOGY
ISSN journal
0748-7983 → ACNP
Volume
27
Issue
7
Year of publication
2001
Pages
626 - 630
Database
ISI
SICI code
0748-7983(200111)27:7<626:ATDIWW>2.0.ZU;2-R
Abstract
Aims: Estimation of prevalence of autoimmune thyroid disorders in Greek bre ast cancer patients (prospective study). Methods: The prevalence of autoimmune thyroiditis was estimated in 310 Gree k breast cancer patients, in 100 women with benign breast disease and in 19 0 women without any breast disease, by submitting them to clinical examinat ion, ultrasound thyroid evaluation, serum thyroid antibody determination an d fine needle aspiration (FNA) of the thyroid gland. Results: Autoimmune thyroiditis was found in 136/310 (43.9%) breast cancer women: 95 were diagnosed by positive autoantibodies, 19 had positive FNA fi ndings and 22 had both positive autoantibodies and positive FNA findings. I n 117 cases, thyroid autoantibodies were positive (37.7% whereas the contro l groups had respective rates of 19% and 18.4% autoantibody positivity). Conclusions: There is evidence of high incidence of autoimmune thyroiditis in Greek breast cancer patients, increasing in relation to cancer stage. (C ) 2001 Harcourt Publishers Ltd.