Autoimmune vesicles on the face and neck. A variant of Brunsting-Perry type localized bullous pemphigoid?

Citation
Y. Sugita et al., Autoimmune vesicles on the face and neck. A variant of Brunsting-Perry type localized bullous pemphigoid?, EUR J DERM, 11(6), 2001, pp. 557-559
Citations number
11
Language
INGLESE
art.tipo
Article
Categorie Soggetti
da verificare
Journal title
EUROPEAN JOURNAL OF DERMATOLOGY
ISSN journal
1167-1122 → ACNP
Volume
11
Issue
6
Year of publication
2001
Pages
557 - 559
Database
ISI
SICI code
1167-1122(200111/12)11:6<557:AVOTFA>2.0.ZU;2-9
Abstract
We report a case of blistering disease presenting a unique distribution of vesiculobullous lesions on the face and neck which is similar to Brunsting- Perry type of localized bullous pemphigoid (BP). Histopathology of a lesion al skin biopsy demonstrated a subepidermal blister. Direct immunofluorescen ce demonstrated a strong linear deposition of IgG and IgA to the basement m embrane zone, and a faint staining for C3. However, circulating antibodies were not detected by indirect immunofluorescence and immunoblotting. And th e patient did not develop atrophic scars and was relatively young woman. Th is case might be a variant of Brunsting-Perry type of localized BP or local ized epidermolysis bullosa acquisita, presenting the clinical heterogeneity of subepidermal blistering diseases.