Naturally occurring 1,2,8-trimethoxyxanthone and biphenyl ether intermediates leading to 1,2-dimethoxyxanthone

Citation
L. Gales et al., Naturally occurring 1,2,8-trimethoxyxanthone and biphenyl ether intermediates leading to 1,2-dimethoxyxanthone, ACT CRYST C, 57, 2001, pp. 1319-1323
Citations number
16
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS
ISSN journal
0108-2701 → ACNP
Volume
57
Year of publication
2001
Part
11
Pages
1319 - 1323
Database
ISI
SICI code
0108-2701(200111)57:<1319:NO1ABE>2.0.ZU;2-G
Abstract
In order to study structure-activity relationships, a series of mono-, di- and trioxygenated xanthones has been synthesized and the structures of meth yl 2-(3,4-dimethoxyphenoxy)benzoate, C16H16O5, 2-(3,4-dimethoxyphenoxy)benz oic acid, C15H14O5, 1,2-dimethoxy-9H-xanthen-9-one, C15H12O4, and 1,2,8-tri methoxy-9H-xanthen-9-one, C16H14O5, have been determined. The first two com pounds both assume skew conformations, the dihedral angles between the two phenyl rings being 80.04 (8) and 83.0 (1)degrees, respectively. The latter two compounds are essentially planar and their methoxy substituents assume orientations consistent with minimum steric interactions.