Importance of intraoperative parathormone measurements for primary hyperparathyroidism with hyperplasia of five glands

Citation
J. Werner et al., Importance of intraoperative parathormone measurements for primary hyperparathyroidism with hyperplasia of five glands, CHIRURG, 72(10), 2001, pp. 1186-1189
Citations number
26
Language
TEDESCO
art.tipo
Article
Categorie Soggetti
Surgery
Journal title
CHIRURG
ISSN journal
0009-4722 → ACNP
Volume
72
Issue
10
Year of publication
2001
Pages
1186 - 1189
Database
ISI
SICI code
0009-4722(200110)72:10<1186:IOIPMF>2.0.ZU;2-S
Abstract
While intraoperative parathormone measurements are mandatory for unilateral operations of primary hyperparathyroidism (pHPT), its value for treatment of parathyroid hyperplasia is regarded as insufficient. We report a case of a pHPT with hyperplasia of five glands, in which only the intraoperative a nalysis of parathormone detected the remaining fifth hyperparathyroid gland after extirpation of four enlarged parathyroid glands. We describe technic al problems involved in the tests available today and how the results of th e intraoperative parathormone test need to be interpreted. As several facto rs can influence the decrease in parathormone concentration, a kinetic anal ysis may be more accurate in assessing the adequacy of resection. Therefore , intraoperative parathormone measurements are especially useful and import ant for adequate surgical therapy for pHPT with parathyroid hyperplasia.