Intraoperative US staging of T in gastric cancer: Final results of a blindprospective study

Citation
G. De Manzoni et al., Intraoperative US staging of T in gastric cancer: Final results of a blindprospective study, J SURG ONC, 78(3), 2001, pp. 158-161
Citations number
28
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Oncology
Journal title
JOURNAL OF SURGICAL ONCOLOGY
ISSN journal
0022-4790 → ACNP
Volume
78
Issue
3
Year of publication
2001
Pages
158 - 161
Database
ISI
SICI code
0022-4790(200111)78:3<158:IUSOTI>2.0.ZU;2-P
Abstract
Background: In order to improve the accuracy in the assessment of depth of tumor invasion, we performed an ultrasound examination of the resected spec imen intraoperatively just after removal by the surgeon (Intraoperative Ult rasonography (IUS). This prospective blind study reports the results obtain ed with the IUS in the staging of T in a group of 281 patients who underwen t curative gastrectomy for gastric cancer. Methods: After the removal by the surgeon, the portion of the stomach harbo ring the tumor was submitted to ultrasonography with a linear 7.5 Mhz probe . An echo-free standoff pad was placed between the probe and the organ; a s econd echo-free standoff pad was interposed between the stomach and the sup port surface. The diagnosis of depth of invasion was based on the degree of disruption of the five-layer sonographic structure of the gastric wall. Results: The IUS staging of T corresponded to the pathological diagnosis in 256 out of 281 cases (overall accuracy 91.1%). The sensitivity in the diff erent classes of T was, respectively, 91.2 in T1m cases, 83.3 in the T1sm c ases, 89.6 in the T2 cases, and 93.5% in the T3 cases. Conclusion: The IUS on the resected specimen has a high degree of accuracy in the assessment of depth of tumor invasion and seems to be an important a dvance in the clinical staging of gastric cancer. (C) 2001 Wiley-Liss, Inc.