Mastocytosis

Citation
Md. Tharp et Bj. Longley, Mastocytosis, DERM CLIN, 19(4), 2001, pp. 679
Citations number
172
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Dermatology
Journal title
DERMATOLOGIC CLINICS
ISSN journal
0733-8635 → ACNP
Volume
19
Issue
4
Year of publication
2001
Database
ISI
SICI code
0733-8635(200110)19:4<679:M>2.0.ZU;2-F
Abstract
Mastocytosis represents a heterogeneous group of clinical disorders resulti ng from the infiltration of mast cells in the skin and other organs. Althou gh mastocytosis was first described over 130 years ago, the pathophysiologi c mechanisms responsible for this disease have been identified only recentl y. This article discusses the salient clinical features of the disease, the mechanisms responsible for its development, and provides treatment approac hes that have proven useful for managing patients with this disorder.