New products for rejuvenation of the skin are increasingly categorized as c
osmeceuticals, with modest data available for evaluation of their efficacy.
Products that appear promising include topical vitamin C and N6-furfurylad
enenine. Retinoids and alpha hydroxyacid remain, however, the cornerstone o
f a physician-directed skin program. Microdermabrasion has gained widesprea
d popularity as an office-based treatment and the available data will be re
viewed.