IM droperidol as premedication attenuates intraoperative hypothermia

Citation
K. Toyota et al., IM droperidol as premedication attenuates intraoperative hypothermia, CAN J ANAES, 48(9), 2001, pp. 854-858
Citations number
21
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Aneshtesia & Intensive Care","Medical Research Diagnosis & Treatment
Journal title
CANADIAN JOURNAL OF ANAESTHESIA-JOURNAL CANADIEN D ANESTHESIE
ISSN journal
0832-610X → ACNP
Volume
48
Issue
9
Year of publication
2001
Pages
854 - 858
Database
ISI
SICI code
0832-610X(200110)48:9<854:IDAPAI>2.0.ZU;2-8
Abstract
Purpose: Perioperative hypothermia results largely from core-to-peripheral heat redistribution. Droperidol, which is often used for premedication, pro motes vasodilation, and thus may affect redistribution of heat, Accordingly , we tested the hypothesis that preanesthetic droperidol would affect perio perative hypothermia. Methods: Twenty-three ASA physical status 1 patients scheduled for arthrosc opic ligament reconstruction were randomly assigned to two groups to receiv e no premedication or im dropendol 0.1 mg(.)kg(-1) 30 min before anesthesia . Anesthesia was induced and maintained with propofol and fentanyl. We moni tored core (tympanic) and peripheral (palm) temperatures, and skin (fingert ip) blood flow for two hours after the induction of anesthesia during surge ry. Results: Before the induction of anesthesia, patients given droperidol were more deeply sedated than those given no premedication. Core temperature, w hich was similar in both groups before induction, decreased significantly m ore in the control than in the droperidol patients (0.75 +/- 0.34 degreesC and 0.37 +/- 0.20 degreesC, respectively, at 75 min after induction; P < 0. 01). Preinduction peripheral temperature and skin blood flow were lower in the control group than in the droperidol group, but the two variables becam e similar in both groups after induction. Conclusion: The results of the present study confirm our hypothesis that pr emedication with droperidol affects perioperative hypothermia. Droperidol m ay prevent core-to-peripheral heat redistribution after the induction of an esthesia.