Subacute myocardial infarction: assessment by STIR T2-weighted MR imaging in comparison to regional function

Citation
S. Miller et al., Subacute myocardial infarction: assessment by STIR T2-weighted MR imaging in comparison to regional function, MAGN RES MA, 13(1), 2001, pp. 8-14
Citations number
30
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging
Journal title
MAGNETIC RESONANCE MATERIALS IN PHYSICS BIOLOGY AND MEDICINE
ISSN journal
0968-5243 → ACNP
Volume
13
Issue
1
Year of publication
2001
Pages
8 - 14
Database
ISI
SICI code
0968-5243(200108)13:1<8:SMIABS>2.0.ZU;2-A
Abstract
Purpose. Increased 72 signal intensity (SI) can be regularly observed in my ocardial infarction. However, there are controversial reports about the rel ationship of elevated T2 SI to myocardial viability and some authors propos e that high T2 SI serves as a sign of irreversible myocardial injury. This study, investigates increased T2 SI compared to myocardial function in pati ents with reperfused subacute myocardial infarction. Preserved function was used as criterion for viability. Methods: Ten healthy volunteers and 17 pa tients with myocardial infarction and patent infarct related coronary arter y were examined on a 1.5 T Magnetom Vision system (Siemens). For T2-weighte d MR imaging a breath-hold STIR sequence with dark-blood preparation was us ed. Cine FLASH 2D imaging was applied to assess myocardial function. Signal -to-noise (SIN) in STIR T2 images was measured in normal and infarcted regi ons and subsequently identified by two independent observers. Based on a 20 segment model of the left ventricle findings were compared to regional myo cardial function. Results: Elevated STIR T2 SI was found in all 17 patients and observed in 27% (204/754) of segments. S/N of normal myocardium was 5. 1 +/-0.7 in volunteers and 4.9 +/-0.8 in patients (P=NS). Infarcted myocard ium presented with significantly increased S/N 12.9 +/-1.9 (F<0.0001). Sign ificant transmural elevation of T2 SI was noted in 32% of segments with pre served systolic function. Conclusion: Increased STIR T2 SI can be observed transmurally in post-ischemic myocardial regions with preserved function. I t therefore cannot be used as an exclusive marker for the non-viable region . (C) 2001 Elsevier Science B.V. All rights reserved.