Membranous proliferation of lens epithelial cells on acrylic, silicone, and poly(methyl methacrylate) lenses

Citation
D. Kurosaka et K. Kato, Membranous proliferation of lens epithelial cells on acrylic, silicone, and poly(methyl methacrylate) lenses, J CAT REF S, 27(10), 2001, pp. 1591-1595
Citations number
18
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Optalmology
Journal title
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
ISSN journal
0886-3350 → ACNP
Volume
27
Issue
10
Year of publication
2001
Pages
1591 - 1595
Database
ISI
SICI code
0886-3350(200110)27:10<1591:MPOLEC>2.0.ZU;2-T
Abstract
Purpose. To determine whether irtraocular lens (IOU material influences the membranous proliferation of lens epithelial cells (LECs) on the anterior s urface of the IOL. Setting. Department of Ophthalmology, Keio University School of Medicine, T okyo, Japan. Methods: This prospective study included 87 eyes of 87 consecutive patients who had cataract surgery with IOL implantation. Patients were randomly ass igned to receive a single-piece poly(methyl methacrylate) (PMMA) IOL, a 3-p iece silicone IOL, or a 3-piece acrylic IOL. Postoperatively, the IOL optic was examined by slitlamp microscopy at 1 and 10 days and 1, 2, and 3 month s to determine the incidence, duration, and extent of membranous LEC prolif eration. The optic was also examined at 6, 9, and 12 months if proliferatio n persisted. Results. Thirteen eyes were excluded from analysis because of incomplete co verage of the IOL rim by the anterior capsule margin; 74 remaining eyes wer e studied. All patients obtained good postoperative visual acuity (20/25 or better). Incidence (P = .0024) and duration (P = .0002) of membranous LEC proliferation with the acrylic IOL was greater than with the other 2 types. Proliferation on the acrylic IOL was more extensive than on the PMMA IOL 1 0 days postoperatively (P < .05) and on the silicone IOL at 10 days (P < .0 1) and 1 month (P < .01). However, LEC proliferation on the 3 types of IOLs usually decreased by the third postoperative month, and proliferation did not disturb visual acuity. Conclusions. The material of an IOL influenced membranous proliferation of LECs on its anterior surface. Proliferation on the acrylic IOL persisted lo nger than on the other 2 types but did not cause visual symptoms. (C) 2001 ASCRS and ESCRS.