Complete response of a stage IV mucinous cystadenocarcinoma of the ovary to systemic chemotherapy employing paclitaxel and carboplatin

Citation
Y. Yokoyama et al., Complete response of a stage IV mucinous cystadenocarcinoma of the ovary to systemic chemotherapy employing paclitaxel and carboplatin, GYNECOL OBS, 52(3), 2001, pp. 210-214
Citations number
18
Language
INGLESE
art.tipo
Article
Categorie Soggetti
da verificare
Journal title
GYNECOLOGIC AND OBSTETRIC INVESTIGATION
ISSN journal
0378-7346 → ACNP
Volume
52
Issue
3
Year of publication
2001
Pages
210 - 214
Database
ISI
SICI code
0378-7346(2001)52:3<210:CROASI>2.0.ZU;2-K
Abstract
Background. The survival rate of patients with advanced-stage mucinous cyst adenocarcinoma of the ovary is dismal and no best treatment is known. We re port a case of complete response of a stage IV mucinous cystadenocarcinoma of the ovary to systemic chemotherapy employing paclitaxel and carboplatin. Case: A 51-year-old nullipara diagnosed with International Federation of G ynecology and Obstetrics stage IV mucinous cystadenocarcinoma of the ovary underwent cytoreductive surgery followed by systemic chemotherapy employing paclitaxel and carboplatin every 4 weeks for 3 courses. The patient tolera ted chemotherapy well, demonstrated a remarkable response showing no eviden ce of malignancy at a second-look laparotomy. As a consolidation chemothera py after negative second-look laparotomy, she underwent another three cours es of chemotherapy of the same regimen, and is showing no evidence of disea se. Conclusion: Paclitaxel and carboplatin may be effective in treating muc inous cystadenocarcinoma of the ovary. Copyright (C) 2001 S. Karger AG, Bas el.