Regulation of nucleocytoplasmic trafficking by cell adhesion receptors andthe cytoskeleton

Citation
Ae. Aplin et Rl. Juliano, Regulation of nucleocytoplasmic trafficking by cell adhesion receptors andthe cytoskeleton, J CELL BIOL, 155(2), 2001, pp. 187-191
Citations number
40
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Cell & Developmental Biology
Journal title
JOURNAL OF CELL BIOLOGY
ISSN journal
0021-9525 → ACNP
Volume
155
Issue
2
Year of publication
2001
Pages
187 - 191
Database
ISI
SICI code
0021-9525(20011015)155:2<187:RONTBC>2.0.ZU;2-N
Abstract
It has become widely accepted that adhesion receptors can either directly a ctivate, or significantly modulate, many of the signaling cascades initiate d by circulating growth factors. An interesting recent development is the r ealization that adhesion receptors and their cytoskeletal partners can regu late the trafficking of signaling proteins between the cytoplasm and nucleu s. Cell adhesion molecule control of nucleocytoplasmic trafficking allows a dhesion to influence many cell decisions, and highlights the diversity of n uclear import and export mechanisms.