The importance of the removal of the intrauterine device in genital colonization by Actinomyces

Citation
I. Bonacho et al., The importance of the removal of the intrauterine device in genital colonization by Actinomyces, GYNECOL OBS, 52(2), 2001, pp. 119-123
Citations number
22
Language
INGLESE
art.tipo
Article
Categorie Soggetti
da verificare
Journal title
GYNECOLOGIC AND OBSTETRIC INVESTIGATION
ISSN journal
0378-7346 → ACNP
Volume
52
Issue
2
Year of publication
2001
Pages
119 - 123
Database
ISI
SICI code
0378-7346(2001)52:2<119:TIOTRO>2.0.ZU;2-N
Abstract
Objective: To determine whether, in addition to treatment with antibiotics, it is necessary to remove the intrauterine device (IUD) to eliminate genit al colonization by Actinomyces. Methods: A randomized clinical trial was ca rried out. Patients were divided into two groups. The intervention group di d not have their IUDs removed, while the control group did. Both groups wer e treated with trimethoprim and sulfamethoxazole. A total of 43 patients we re included. Results: The patients from the intervention group and the cont rol group proved to be comparable. The post-intervention cytology smear tes ted negative for Actinomyces in 100% of the patients whose IUD had been rem oved and in 66.7% of those whose IUD had not been removed (p = 0.005). The probability that colonization by Actinomyces will continue if the IUD is no t removed is greater the longer the patient has been exposed to the IUD. Af ter 24 months, relative risk (RR) = 2, after 36 months RR = 2.16 and after 48 months RR = 2.66. Conclusions: The removal of the IUD has been effective in genital colonization by Actinomyces. The protective effect exerted by t he removal of the IUD was found to be greater in proportion to the length o f time the patient had used it. Copyright (C) 2001 S. Karger AG, Basel.