Cell manipulation by use of diamond microparticles as handles of optical tweezers

Citation
Ck. Sun et al., Cell manipulation by use of diamond microparticles as handles of optical tweezers, J OPT SOC B, 18(10), 2001, pp. 1483-1489
Citations number
27
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Apllied Physucs/Condensed Matter/Materiales Science","Optics & Acoustics
Journal title
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA B-OPTICAL PHYSICS
ISSN journal
0740-3224 → ACNP
Volume
18
Issue
10
Year of publication
2001
Pages
1483 - 1489
Database
ISI
SICI code
0740-3224(200110)18:10<1483:CMBUOD>2.0.ZU;2-J
Abstract
We report the experimental results of our using irregularly shaped diamond microparticles as handles for laser tweezers. Because of their irregular op tical shape, control of the rotation of diamond microparticles can easily b e achieved in a gradient force optical trap by use of a fixed linearly pola rized beam with a fundamental Gaussian mode. By changing the laser focal pl ane upon a diamond particle near the liquid surface or interfaces, one can fully manipulate both the direction and speed of the rotation. The ability to manipulate a diamond-particle-tagged biological specimen by optical twee zers is discussed. The application of these particles as handles for optica l tweezers is demonstrated by optical manipulation of biological cells. Ind ependent movement of linear translation and rotation, with controllable rot ation directions and speeds, is successfully achieved. (C) 2001 Optical Soc iety of America.