We subjected the first replication of the simulated isolated population dat
a set to a novel analysis for association between marker alleles and either
disease phenotypes or quantitative variable. The analysis depends on being
able to reliably reconstruct all haplotypes in the pedigree. This was achi
eved using the MCLINK blocked Gibbs sampling program. We observed a highly
significant association between the variable Q5 and marker D01G138, and sug
gestive associations between the disease trait and markers D03G056 and D07G
004. (C) 2001 Wiley-Liss, Inc.