Pallidal activity is involved in visuomotor association learning in monkeys

Citation
M. Inase et al., Pallidal activity is involved in visuomotor association learning in monkeys, EUR J NEURO, 14(5), 2001, pp. 897-901
Citations number
18
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Neurosciences & Behavoir
Journal title
EUROPEAN JOURNAL OF NEUROSCIENCE
ISSN journal
0953-816X → ACNP
Volume
14
Issue
5
Year of publication
2001
Pages
897 - 901
Database
ISI
SICI code
0953-816X(200109)14:5<897:PAIIIV>2.0.ZU;2-V
Abstract
In order to examine whether the basal ganglia are involved in arbitrary vis uomotor association, we recorded neuronal activity in the internal segment of the globus pallidus (GPi) of monkeys during a conditional visuomotor lea rning task. Two monkeys were presented a cueing visual stimulus, and follow ing a delay period required to push, pull or turn a manipulator according t o the cue. GPi neurons showed changes in activity during the delay period w hen the animals performed the task on the basis of a familiar stimulus-resp onse association. Those changes in delay activity were enhanced as the monk eys were learning a new visuomotor association. The enhancement of the chan ges was selective to a following response. These results suggest that the b asal ganglia are involved in arbitrary visuomotor association, especially d uring the learning of new associations.