Lymphocyte development from hematopoietic stem cells

Citation
M. Kondo et al., Lymphocyte development from hematopoietic stem cells, CUR OP GEN, 11(5), 2001, pp. 520-526
Citations number
54
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Cell & Developmental Biology
Journal title
CURRENT OPINION IN GENETICS & DEVELOPMENT
ISSN journal
0959-437X → ACNP
Volume
11
Issue
5
Year of publication
2001
Pages
520 - 526
Database
ISI
SICI code
0959-437X(200110)11:5<520:LDFHSC>2.0.ZU;2-H
Abstract
The recent application of new techniques, such as multi-color cell sorting and the production of transgenic and gene-knockout mice, has contributed to a better understanding of lymphocyte development from hematopoietic stem c ells. New that we can purify progenitors at different maturational stages d uring lymphocyte development, the challenge is to understand the processes that govern each developmental stage transition.