The presentation, aetiology, management and outcome of optic neuritis in an Asian population

Citation
Jc. Wang et al., The presentation, aetiology, management and outcome of optic neuritis in an Asian population, CLIN EXP OP, 29(5), 2001, pp. 312-315
Citations number
10
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Optalmology
Journal title
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
ISSN journal
1442-6404 → ACNP
Volume
29
Issue
5
Year of publication
2001
Pages
312 - 315
Database
ISI
SICI code
1442-6404(200110)29:5<312:TPAMAO>2.0.ZU;2-G
Abstract
Purpose: To analyse the presentation, aetiology, management and outcome of patients with optic neuritis (ON) in Singapore. Methods: This was a retrospective study involving consecutive patients with ON presenting at the Singapore National Eye Centre between January 1997 an d May 1999. The presenting features, investigations, treatment and visual o utcome after 6 months were studied. Results: A total of 31 patients (39 eyes) presented with ON during this per iod, 17 of whom had anterior ON. No aetiology was found in 26 patients (83. 9%), two patients (6.5%) had multiple sclerosis, one had active syphilis, o ne had rheumatoid arthritis and another had pan-sinusitis. Seventeen patien ts (54.8%) were treated with intravenous methyl-prednisolone followed by or al prednisolone. Within the follow-up period 26 of 31 eyes (83.9%) with idi opathic ON attained visual acuity of 6/12 or better, with 12 (38.7%) recove ring to 6/6 or better and only one eye ending with less than 6/60 visual ac uity. The one patient with syphilis recovered 6/6 visual acuity bilaterally . Both patients with multiple sclerosis also had good visual recovery at 6 months. The visual outcome in those cases of ON associated with rheumatoid arthritis and pan-sinusitis was poor with visual acuity of less than 6/60 a t 6 months follow up in each instance. Conclusion: The majority of the cases of ON in this study were idiopathic. There was a low association with multiple sclerosis. Most patients had good visual recovery within 6 months.