Cyanobacteria exhibit numerous responses to changes in the intensity and sp
ectral quality of light. What sensors do cyanobacteria use to detect light
and what are the mechanisms of signal transduction? The publication in 1996
of the complete genome sequence of the cyanobacterium Synechocystis 6803 p
rovided a tremendous stimulus for research in this field, and many light-se
nsors and signal transducers have now been identified. However, our knowled
ge of cyanobacterial light-signal transduction remains fragmentary. This re
view summarizes what we know about the ways in which cyanobacteria perceive
light, some of the ways which they respond to light signals and some recen
t achievements in elucidating the signal transduction mechanisms. Some prob
lems in characterizing cyanobacterial signal transduction pathways are outl
ined and alternative experimental strategies are discussed.