Radiosurgery-induced brain tumor - Case report

Citation
T. Kaido et al., Radiosurgery-induced brain tumor - Case report, J NEUROSURG, 95(4), 2001, pp. 710-713
Citations number
25
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
JOURNAL OF NEUROSURGERY
ISSN journal
0022-3085 → ACNP
Volume
95
Issue
4
Year of publication
2001
Pages
710 - 713
Database
ISI
SICI code
0022-3085(200110)95:4<710:RBT-CR>2.0.ZU;2-A
Abstract
The authors describe a case of glioblastoma multiforme (GBM) associated wit h previous gamma knife radiosurgery for a cerebral arteriovenous malformati on (AVM). A 14-year-old boy had undergone radiosurgery for an AVM, which wa s performed using a 201-source Co-60 gamma knife system at another institut ion. The maximum and margin radiation doses used in the procedure were 40 a nd 20 Gy, respectively. One year after radiosurgery, the patient noticed on set of mild left hemiparesis due to radiation necrosis. Six and one-half years after radiosurgery, at the age of 20 years, the pati ent experienced an attack of generalized tonic-clonic seizure. Magnetic res onance (MR) imaging revealed the existence of a brain tumor in the right pa rietal lobe. The patient underwent an operation and the histological diagno sis of the lesion was GBM. Ten months following the operation, that is, 99 months postradiosurgery, this patient died. To the best of the authors' knowledge, this is the first reported case of a neoplasm induced by radiosurgery for an AVM and the second case in which i t occurred following radiosurgery for intracranial disease.