Cytological diagnosis of primary leiomyosarcoma of bone: Case report

Citation
I. Cohen et al., Cytological diagnosis of primary leiomyosarcoma of bone: Case report, DIAGN CYTOP, 25(4), 2001, pp. 239-243
Citations number
10
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology
Journal title
DIAGNOSTIC CYTOPATHOLOGY
ISSN journal
8755-1039 → ACNP
Volume
25
Issue
4
Year of publication
2001
Pages
239 - 243
Database
ISI
SICI code
8755-1039(200110)25:4<239:CDOPLO>2.0.ZU;2-7
Abstract
We report on a case of primary leiomyosarcoma of the bone in a 77-yr-old ma n. The patient presented with a painful, enlarging mass in the left shoulde r of 6 mo duration. Radiography and computed tomography (CT) revealed a lar ge destructive intramedullary lesion of the proximal humerus, with massive extension into the surrounding soft tissues. CT-guided fine-needle aspirati on biopsies (FNAB) of both the bony and soft-tissue lesions were performed. Cytological examination showed a neoplastic process composed of spindle ce lls mixed with pleomorphic cells. The smooth muscle origin of the neoplasti c cells was confirmed by immunocytochemical analysis. We describe the cytol ogical features of this rare primary tumor of bone, and consider the differ ential diagnosis of spindle-cell neoplasms. (C) 2001 Wiley-Liss, Inc.