Distribution of Pneumocystis carinii f. sp. hominis types in the lung of achild dying of Pneumocystis pneumonia

Citation
He. Ambrose et al., Distribution of Pneumocystis carinii f. sp. hominis types in the lung of achild dying of Pneumocystis pneumonia, CLIN INF D, 33(9), 2001, pp. E100-E102
Citations number
10
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL INFECTIOUS DISEASES
ISSN journal
1058-4838 → ACNP
Volume
33
Issue
9
Year of publication
2001
Pages
E100 - E102
Database
ISI
SICI code
1058-4838(20011101)33:9<E100:DOPCFS>2.0.ZU;2-D
Abstract
Pneumocystis f. sp. hominis causes pneumonia in immunocompromised persons. In order to determine the types and distribution of P. carinii organisms wi thin a single human lung, multiple samples were obtained from the lung of a child who died of P. carinii pneumonia. P. carinii DNA was detected in all of the samples and 2 different genotypes of P. carinii were identified, wi th uneven distribution in the lung, demonstrating that infection of the hum an lung is not necessarily clonal, and that different P. carinii genotypes may predominate in different areas of the lung.