Evaluation of use of a single intravaginal swab to detect multiple sexually transmitted infections in active-duty military women

Citation
Am. Rompalo et al., Evaluation of use of a single intravaginal swab to detect multiple sexually transmitted infections in active-duty military women, CLIN INF D, 33(9), 2001, pp. 1455-1461
Citations number
24
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
CLINICAL INFECTIOUS DISEASES
ISSN journal
1058-4838 → ACNP
Volume
33
Issue
9
Year of publication
2001
Pages
1455 - 1461
Database
ISI
SICI code
1058-4838(20011101)33:9<1455:EOUOAS>2.0.ZU;2-T
Abstract
The accuracy and suitability of use of a single intravaginal swab (SIS) for polymerase chain reaction detection of Neisseria gonorrhoeae, Chlamydia tr achomatis, Trichomonas vaginalis, and human papillomavirus infection was as sessed in a cross-sectional study of 841 active-duty military women. The SI S, compared with standard diagnostic tests, allowed detection of more gonor rhea, more chlamydial infection, and more trichomoniasis. Sensitivity and s pecificity of SIS detection compared with adjudicated true-positive diagnos es were 95.8% and 97.8%, respectively, for gonorrhea, 94.6% and 99.3% for c hlamydial infection, and 92.2% and 98.2% for trichomonal infection. Results with SISs were comparable to those with cervical swabs tested for human pa pillomavirus. Assay of clinician-collected and self-collected SISs yielded prevalences similar to those of standard diagnostic tests for all sexually transmitted infections. Therefore, the use of SISs is acceptable for the si multaneous diagnosis of multiple sexually transmitted infections and has po tential for use as a self-administered diagnostic tool with widespread appl icability among women.