First example of supported microwave-assisted synthesis of new chiral bipyridines and a terpyridine - Use in asymmetric cyclopropanation

Citation
F. Pezet et al., First example of supported microwave-assisted synthesis of new chiral bipyridines and a terpyridine - Use in asymmetric cyclopropanation, EUR J INORG, (10), 2001, pp. 2669-2674
Citations number
34
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
ISSN journal
1434-1948 → ACNP
Issue
10
Year of publication
2001
Pages
2669 - 2674
Database
ISI
SICI code
1434-1948(200110):10<2669:FEOSMS>2.0.ZU;2-J
Abstract
We present herein the first alumina-supported synthesis of chiral bipyridin es and of a chiral C2-symmetric terpyridine conducted under microwave irrad iation, and our preliminary results from copper-mediated enantioselective c yclopropanation with this terpyridine, Reaction yields were excellent and e nantioselectivities of up to 87% were observed. Moreover, with trans-beta - methylstyrene, a remarkable diastereoselectivity (ratio trans/cis = 7:93) w as observed.