Role of the water as a surface tension modifier for the retention of a series of dansylaminoacids on a beta-CD stationary phase

Citation
Yc. Guillaume et al., Role of the water as a surface tension modifier for the retention of a series of dansylaminoacids on a beta-CD stationary phase, TALANTA, 55(2), 2001, pp. 263-269
Citations number
32
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
TALANTA
ISSN journal
0039-9140 → ACNP
Volume
55
Issue
2
Year of publication
2001
Pages
263 - 269
Database
ISI
SICI code
0039-9140(20010830)55:2<263:ROTWAA>2.0.ZU;2-O
Abstract
In reversed phase liquid chromatography (RPLC), using a surface tension tre atment, the retention and separation of a series of D,L-dansylaminoacids we re investigated with native beta -cyclodextrin as a chiral stationary phase . The enantioselectivity thermodynamic parameters were determined from line ar van't Hoff plots. An analysis of the experimental variations in the rete ntion factor with different fractions of water in the mobile phase was perf ormed. The number of water molecules, n. excluded from the solute beta -cyc lodextrin cavity interface when the analyte transfer occurred, was determin ed. Using these n values, the relative degrees of compound inclusion were c alculated and correlated to both the steric bulkiness of the solute and the thermodynamic data. (C) 2001 Elsevier Science B.V. All rights reserved.