Spontaneous regression of hepatic adenoma in a patient with glycogen storage disease type I after hemodialysis: Ultrasonographic and CT findings

Citation
H. Iijima et al., Spontaneous regression of hepatic adenoma in a patient with glycogen storage disease type I after hemodialysis: Ultrasonographic and CT findings, INTERN MED, 40(9), 2001, pp. 891-895
Citations number
9
Language
INGLESE
art.tipo
Article
Categorie Soggetti
General & Internal Medicine
Journal title
INTERNAL MEDICINE
ISSN journal
0918-2918 → ACNP
Volume
40
Issue
9
Year of publication
2001
Pages
891 - 895
Database
ISI
SICI code
0918-2918(200109)40:9<891:SROHAI>2.0.ZU;2-K
Abstract
A 23-year-old woman was admitted to our hospital with recurrent gouty arthr itis. Laboratory findings showed hypoglycemia, lactic acidosis, hyperlipide mia, and hyperuricemia, with normal values of serum alfa-fetoprotein (AFP) and protein induced by vitamin K absence (PIVKA-II). A diagnosis of glycoge n storage disease type I (GSD-type I) was made on the basis of the laborato ry data, liver biopsy findings, and partially deficient thrombocyte glucose -6-phosphatase (G-6-Pase) activity. Ultrasonography and computed tomography revealed multiple focal hepatic masses. Biopsied specimens of the lesion d emonstrated a hepatic adenoma, which changed in appearance in the relativel y short period between echography and computed tomography. This interesting phenomenon may highlight the importance for careful follow-up of hepatic a denomas, because of the potential of rapture, hemorrhage, or malignant tran sformation. During follow-up, the present patient received hemodialysis due to renal failure, and the adenoma regressed spontaneously after 8 years. I ncluded are diagnostic images, demonstrating the association of hepatic ade noma. and GSD-type I.