Stereoselective synthesis of 4H-5,6-dihydro-1,3-thiazines by the reaction of 3-N-acylamino alcohols with Lawesson's reagent

Citation
T. Nishio et al., Stereoselective synthesis of 4H-5,6-dihydro-1,3-thiazines by the reaction of 3-N-acylamino alcohols with Lawesson's reagent, EUR J ORG C, (18), 2001, pp. 3553-3557
Citations number
34
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
1434-193X → ACNP
Issue
18
Year of publication
2001
Pages
3553 - 3557
Database
ISI
SICI code
1434-193X(200109):18<3553:SSO4BT>2.0.ZU;2-G
Abstract
The 4H-5,6-Dihydro-1,3-thiazine derivatives 13-15 were obtained exclusively and stereoselectively in fair yields by treating the 3-N-acylamino alcohol s 5-8 with an equimolar amount of Lawesson's reagent (LR), while the corres ponding thiols 9-12 were afforded stereoselectively when only 0.5 equiv. of LR was used in this reaction.