S. Sengupta et al., Zinc borohydride reduction of alpha-amino ketones: A highly diastereoselective synthetic route to anti-gamma-hydroxy-beta-amino alcohols, SYNLETT, (9), 2001, pp. 1464-1466
A highly diastereoselective synthesis of anti-gamma -hydroxy-beta -amino al
cohols via Zn(BH4)(2) reductions of serine derived alpha -amino ketones is
described. The latter were prepared from a serine derived gamma -amino-beta
-ketosulfone via a alpha -alkylation-desulfonation sequence.