Cell apoptosis induced by carcinogenic metals

Citation
F. Chen et al., Cell apoptosis induced by carcinogenic metals, MOL C BIOCH, 222(1-2), 2001, pp. 183-188
Citations number
53
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Cell & Developmental Biology
Journal title
MOLECULAR AND CELLULAR BIOCHEMISTRY
ISSN journal
0300-8177 → ACNP
Volume
222
Issue
1-2
Year of publication
2001
Pages
183 - 188
Database
ISI
SICI code
0300-8177(200106)222:1-2<183:CAIBCM>2.0.ZU;2-P
Abstract
Well-documented evidence suggests that environmental and occupational expos ure of toxic metals or metal-containing compounds can cause a number of hum an diseases, including inflammation and cancer, through DNA damage, protein modifications, or lipid peroxidation. This mini-review addresses the mecha nisms of cell death induced by some carcinogenic metals, including arsenic (III), chromium (VI) and vanadium (V). A possible contribution of reactive oxygen species to metal-induced cell death is also discussed.