Experimental paratuberculosis in calves following inoculation with a rabbit isolate of Mycobacterium avium subsp paratuberculosis

Citation
Pm. Beard et al., Experimental paratuberculosis in calves following inoculation with a rabbit isolate of Mycobacterium avium subsp paratuberculosis, J CLIN MICR, 39(9), 2001, pp. 3080-3084
Citations number
20
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Microbiology
Journal title
JOURNAL OF CLINICAL MICROBIOLOGY
ISSN journal
0095-1137 → ACNP
Volume
39
Issue
9
Year of publication
2001
Pages
3080 - 3084
Database
ISI
SICI code
0095-1137(200109)39:9<3080:EPICFI>2.0.ZU;2-I
Abstract
The role of wildlife species in the epidemiology of paratuberculosis has be en the subject of increased research efforts following the discovery of nat ural paratuberculosis in free-living rabbits from farms in east Scotland. T his paper describes the experimental inoculation of young calves with an is olate of Mycobacterium avium subsp. paratuberculosis recovered from a free- living rabbit. After a 6-month incubation period, all eight calves inoculat ed with the rabbit isolate had developed histopathological and/or microbiol ogical evidence of M. avium subsp. paratuberculosis infection. Similar resu lts were obtained from a group of calves infected with a bovine isolate of M. avium subsp. paratuberculosis. The virulence of the rabbit isolate for c alves demonstrated in this study suggests that rabbits are capable of passi ng paratuberculosis to domestic ruminants and that wildlife reservoirs of M . avium subsp. paratuberculosis should therefore be considered when formula ting control plans for the disease.