Multi-resistance to antimicrobial agents for the ten most frequently isolated bacterial pathogens

Citation
Ac. Fluit et al., Multi-resistance to antimicrobial agents for the ten most frequently isolated bacterial pathogens, INT J ANT A, 18(2), 2001, pp. 147-160
Citations number
15
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Microbiology
Journal title
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
ISSN journal
0924-8579 → ACNP
Volume
18
Issue
2
Year of publication
2001
Pages
147 - 160
Database
ISI
SICI code
0924-8579(200108)18:2<147:MTAAFT>2.0.ZU;2-M
Abstract
Cross-resistance and multi-resistance to selected antibiotics was determine d for Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, Pseudo monas aeruginosa, Staphylococcus aureus, Staphylococcus epidermidis, Entero coccus faecalis, Streptococcus pneumoniae, Haemophilus influenzae and Morax ella catarrhalis. Amikacin-resist ant Enterobacteriaceae often showed cross -resistance to beta -lactam antibiotics. Only 1% of the Escherichia coli is olates showed resistance to more than four antibiotics from a set of seven. This rate was higher for other Enterobacteriaceae and there were high leve ls of cross-resistance for P. aeruginosa. The cross-resistance of oxacillin with other antibiotics is well known in staphylococci. Penicillin-resistan t pneumococcal isolates were cross-resistant to macrolides. Cross-resistanc e was only a minor problem in H. influenzae and M. catarrhalis. Cross- and multi-resistance are important problems for Gram-negative and Gram-positive bacteria but not for fastidious bacteria with the exception of penicillin- resistant S. pneumoniae. (C) 2001 Elsevier Science B.V. and International S ociety of Chemotherapy. All rights reserved.