Optical biosensors. Monitoring studies of glycopeptide antibiotic fermentation using white light interference

Citation
R. Tunnemann et al., Optical biosensors. Monitoring studies of glycopeptide antibiotic fermentation using white light interference, ANALYT CHEM, 73(17), 2001, pp. 4313-4318
Citations number
23
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis","Spectroscopy /Instrumentation/Analytical Sciences
Journal title
ANALYTICAL CHEMISTRY
ISSN journal
0003-2700 → ACNP
Volume
73
Issue
17
Year of publication
2001
Pages
4313 - 4318
Database
ISI
SICI code
0003-2700(20010901)73:17<4313:OBMSOG>2.0.ZU;2-0
Abstract
This paper describes the design, characterization, and use of an optical bi osensor suited for the process control of biotechnological processes. The d etector principle is based on reflectometric interference spectroscopy (RIf S). RIfS enables a label-free, product-specific monitoring, with a future o utline for on-line process control. The potential of the RUS biosensor is e xemplified by the qualitative and quantitative monitoring of the microbial production of vancomycin-type glycopeptide antibiotics.