DNA sequence recognition by NF kappa B p50 homodimer: Strict and obscure recognition sites in the binding sequence

Citation
A. Kittaka et al., DNA sequence recognition by NF kappa B p50 homodimer: Strict and obscure recognition sites in the binding sequence, NUCLEOS NUC, 20(4-7), 2001, pp. 669-672
Citations number
16
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Biochemistry & Biophysics
Journal title
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS
ISSN journal
1525-7770 → ACNP
Volume
20
Issue
4-7
Year of publication
2001
Pages
669 - 672
Database
ISI
SICI code
1525-7770(2001)20:4-7<669:DSRBNK>2.0.ZU;2-O
Abstract
5-Formyl- and 5-(formylmethyl)-2'-deoxyuridines are introduced into a kappa B site instead of thymidine(s) in order to understand target sequence speci ficity of NF kappaB. It was found that one thymidine in the kappaB site is particularly important for the sequence specific recognition by NF kappaB.